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Sitomet 50/500 | 1 Strip

Name: Sitomet 50/500 | 1 Strip
Brand: ACI Limited
SKU: 10760
Price: 188 BDT
Availability: InStock
Rating: 4.8 (86 reviews)

ACI Limited

Generic: Sitagliptin + Metformin Hydrochloride

Type: Tablet

Pack Size: 10 Pcs

Tablet

10 Pcs

৳ 200 ৳ 188

Sitagliptin (DPP-4 inhibitor): Prolongs action of incretin hormones (GLP-1 & GIP), enhancing insulin release and suppressing glucagon in a glucose-dependent manner.

Metformin (Biguanide): Lowers hepatic glucose output, reduces intestinal glucose absorption, and improves peripheral glucose uptake & utilization.
👉 Together, they provide complementary mechanisms for better glycemic control.

Discount Price: ৳ 188

MRP: ৳ 200 6% Off

🎉 Save ৳: 12 in this Product

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Cash on Delivery - All over Bangladesh
Regular Delivery - 12-24 Hours, Dhaka City* Charge Tk.39-59
Regular Delivery - 24-48 Hours, Other Cities* Charge Tk.99-110

ফ্রি ডেলিভারিঃ - ৯৯৯ টাকা+ অর্ডারে, ঢাকা শহরে
ফ্রি ডেলিভারিঃ - ২৯৯৯ টাকা+ অর্ডারে, ঢাকার বাহিরে

✅ Description:

Adjunct to diet and exercise for glycemic control in adults with type 2 diabetes mellitus where both sitagliptin and metformin therapy is appropriate.

⚠️ Not effective in type 1 diabetes or diabetic ketoacidosis.
⚠️ Safety not established in patients with history of pancreatitis.

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✔️ Dosage & Administration

Film-coated tablet:

Max: Sitagliptin 100 mg + Metformin 2000 mg daily.

Usually twice daily with meals; start low and escalate gradually to minimize GI side effects.

New patients: 50/500 mg twice daily, titrate as tolerated.

Patients already on metformin: dose adjusted to match current regimen.

Extended-release tablet:

Once daily with evening meal.

Max: Sitagliptin 100 mg + Metformin XR 2000 mg.

Patients on multiple XR tablets should take both together once daily.

With insulin/secretagogues: May require lower insulin or sulfonylurea dose to avoid hypoglycemia

✔️ Side Effects

Common: Diarrhea, nausea/vomiting, abdominal discomfort, headache, URTI, nasopharyngitis.

Combination therapy: Hypoglycemia (when used with sulfonylurea/insulin).

Rare: Hypersensitivity reactions (angioedema, anaphylaxis, Stevens-Johnson syndrome).

✔️ Drug Interactions

Cationic drugs (renal elimination): Use cautiously.

Phenprocoumon: Metformin may reduce anticoagulant effect – monitor INR.

Levothyroxine: Can decrease hypoglycemic effect of metformin – monitor glucose levels.

✔️ Contraindications

Renal impairment (elevated serum creatinine or reduced clearance).

Acute or chronic metabolic acidosis (incl. ketoacidosis).

History of hypersensitivity to sitagliptin, metformin, or formulation.

Temporary discontinuation required before iodinated contrast procedures.

✔️ Pregnancy & Lactation

Category B. Use only if clearly needed during pregnancy.

Unknown if excreted in human milk → caution in nursing mothers.

✔️ Precautions & Warnings

Risk of lactic acidosis (especially in renal/hepatic impairment, alcohol abuse, dehydration, sepsis, CHF).
Monitor renal function before initiation and periodically.
May lower Vitamin B12 levels with long-term use → check if neuropathy develops.
Reported cases of pancreatitis; discontinue if suspected.
Use with caution in patients with thyroid disorders, liver disease, or alcohol use.
May require temporary insulin therapy during stress, fever, surgery, or infection.

✔️ Storage

Store below 25°C, in a cool dry place, protected from light.

Keep out of reach of children.

Use only on prescription of a registered physician.

Frequently Asked Questions (FAQ)

+ Q. Q: Will a higher dose work better?

A: No. Taking more than the prescribed dose can increase the risk of side effects and toxicity. If your blood sugar is not controlled, consult your doctor for a dose adjustment or alternative treatment.

+ Q. Q: What is Sitomet Tablet used for?

A: It is an oral antidiabetic medicine prescribed as an add-on to diet and exercise to control blood sugar levels in patients with type 2 diabetes mellitus.

+ Q. Q: What should I do if I miss a dose?

A: Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed one and continue your regular schedule. Do not double the dose.

+ Q. Q: What should I do if I experience low blood sugar?

A: If you feel hungry, sweaty, shaky, weak, or notice a fast/irregular heartbeat, take a sugary snack or sweet drink immediately. Keep glucose or candies handy.

+ Q. Q: How and when should I take it?

A: Take Sitomet Tablet after meals or as directed by your doctor. Swallow it whole with water; do not crush or chew. The exact dose and duration will be decided by your doctor based on your age, weight, and medical condition.

+ Q. Q: What are the common side effects?

A: Possible side effects include low blood sugar (hypoglycemia), stomach upset, constipation, flatulence, metallic taste, sore throat, runny/stuffy nose, and joint pain.

+ Q. Q: What is the best time to take Sitomet?

A: It is best taken with meals to reduce gastrointestinal side effects.

+ Q. Q: Can I stop taking it on my own?

A: No. Stopping the medicine without medical advice may cause your symptoms to return. Always consult your doctor first.

+ Q. Q: How long do I need to continue this medicine?

A: Continue taking it as long as your doctor recommends. Do not stop suddenly, as it may cause your blood sugar to rise again.

+ Q. Q: Does it cause constipation?

A: Yes, constipation may occur. To manage this, eat fiber-rich foods (fruits, vegetables, cereals), drink plenty of water, and stay physically active.

+ Q. Q: Is Sitomet safe in pregnancy?

A: No, it is not recommended during pregnancy. Inform your doctor if you are pregnant or planning to conceive.

+ Q. Q: How much should I take?

A: Take only the dose prescribed by your doctor. Self-adjustment is not advised.

+ Q. Q: Can it be taken with insulin?

A: Using it along with insulin may increase the risk of hypoglycemia. Your doctor will decide if this combination is suitable for you.

+ Q. Q: Can I take it with medicines for high blood pressure?

A: Consult your doctor before combining Sitomet with blood pressure medicines to avoid possible interactions.

+ Q. Q: What precautions should I follow?

A: Inform your doctor if you have kidney, liver, or heart problems, high cholesterol, severe infections, or if you recently had dehydration from vomiting/diarrhea. Follow a healthy diet and exercise plan as advised for better results.

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⚠️Disclaimer:

At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.

📦Pricing Information, Availability:

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